Patrick Galen Dempsey (born January 13, 1966) is an American actor, known for his role as neurosurgeon Dr. Derek Shepherd ("McDreamy") on the medical drama Grey's Anatomy. Prior to Grey's Anatomy, he made several television appearances, earning him an Emmy Award nomination. He has also recently appeared in several films, including Sweet Home Alabama, The Emperor's Club, Freedom Writers, Enchanted, Made of Honor, and Valentine's Day. Dempsey was born in Lewiston, Maine, and grew up in Buckfield, Maine, the youngest of three children born to Amanda and William Dempsey. He has Irish ancestry. He attended Buckfield High School and St. Dominic Regional High School. He was an adept juggler, tying for second in a national juggling competition. He was also an accomplished skier and while in high school won the Maine state slalom championship. Dempsey spent some of his school years in the town of Turner, Maine, where he attended Leavitt Area High School in the Maine School Administrative District 52 (MSAD #52) for his freshman through junior years. As a child, Dempsey attended Camp Wekeela located in Hartford, Maine. Dempsey was diagnosed with dyslexia at age twelve. He told Barbara Walters on her 2008 Oscar special that he thinks dyslexia "made him what he is today." “It’s given me a perspective of — you have to keep working,” Dempsey told Walters. “I have never given up.”

Dempsey was discovered by an invitation to audition for a role in the stage production of Torch Song Trilogy. His audition was successful, and he spent the following four months touring with the company in Philadelphia. Dempsey also appeared on ABC family on a show Overnight Success by Teri DeSario, where he sings and juggles. He followed this with another tour, Brighton Beach Memoirs, in the lead role, which was directed by Gene Saks. Dempsey has also made notable appearances in the stage productions of On Golden Pond, with the Maine Acting Company, and as Timmy (the Martin Sheen role) in a 1990 Off-Broadway revival of The Subject Was Roses co-starring with John Mahoney and Dana Ivey at the Roundabout Theatre in New York. Dempsey's first major feature film role was at age 21 with Beverly D'Angelo in the movie In The Mood, the real life WW2 story about Ellsworth Wisecarver who had relationships with older married women which created a national uproar. This was followed by the teen comedy Can't Buy Me Love in 1987 with actress Amanda Peterson and Some Girls with Jennifer Connelly in 1988. This film was a flop. In 1989, he had the lead role in the film Loverboy with actress Kirstie Alley and Happy Together with actress Helen Slater. Although the teen comedy and romance roles led to Dempsey being somewhat typecast for a time, he was able to avoid playing the same character as his career progressed

Dempsey made a number of featured appearances in television in the 1990s; he was cast several times in pilots that were not picked up for a full season, including lead roles in the TV versions of the films The Player and About A Boy. However he received good reviews[citation needed] as he portrayed real-life mob boss, Meyer Lansky in 1991, when Mobsters was put on the screen. His first major television role was a recurring role as Will's closeted sportscaster boyfriend on Will & Grace. He went on to play the role of Aaron Brooks, Lily & Judy's psychologically unbalanced brother, on Once & Again. Dempsey received an Emmy nomination in 2001 as Outstanding Guest Actor in a Drama Series for the role of Aaron. In 1993, he played a young John F. Kennedy in the 2-part TV mini-series JFK: Reckless Youth. In 2004, he co-starred in the highly acclaimed HBO production, Iron Jawed Angels, opposite Hilary Swank and Anjelica Huston. He also appeared as special guest star in The Practice for 3 episodes finale season (8x13-8x15), as a married man who murdered his lover. Dempsey had a high-profile role as the fiance of Reese Witherspoon's character in Sweet Home Alabama.

He also had a role as Detective Kincaid on Scream 3. When Scream 4 was officially announced, it was speculated Dempsey would return. But in late April, writer Kevin Williamson confirmed the 3 main cast members who had survived the other 3 movies were the only returning characters. Dempsey's most recent roles include the 2007 Disney film Enchanted, and the Paramount Pictures film Freedom Writers where he reunites with his Iron Jawed Angels co-star Hilary Swank. He also voiced the character Kenai in Brother Bear 2. Dempsey starred in the 2008 film Made of Honor as Tom, and appeared in 2010's romantic comedy Valentine's Day; the latter film, directed by Garry Marshall, follows five interconnecting stories about Los Angelinos anticipating (or in some cases dreading) the holiday of love. Dempsey has acquired the rights to the prize-winning novel The Art of Racing in the Rain and will produce and star in the screen version. The film will go into production in 2010. He has also signed on to star in the 2011 movie Transformers: Dark of the Moon. Dempsey has received significant public attention for his role as Dr. Derek Shepherd in the drama Grey's Anatomy. Prior to landing the role of Derek Shepherd, Dempsey auditioned for the role of Dr. Gregory House on another medical show, House.

Initially a midseason replacement, the show was very well received and has become a highly rated program. Media attention has been focused on Dempsey's character Derek, often referred to as "McDreamy", for his sex appeal and the character's romance with intern Meredith Grey (played by Ellen Pompeo). Also in a one-off episode of Private Practice, playing the same character as in Grey's Anatomy. Dempsey was nominated for Best Performance by an Actor in a Television Series – Drama at the 2006 Golden Globes for the role. His success on the show has led to his becoming a spokesman for Mazda and State Farm Insurance. He has been the face of L'Oreal and Versace and was featured in ads for Serengeti sun glasses. In November 2008 he launched an Avon fragrance named Unscripted, and due to its success a second fragrance named Patrick Dempsey 2 was launched in October 2009. He has been married twice. In 1987, he married actress and acting coach Rocky Parker (born 26 February, 1939 in Brooklyn, New York), who appeared with Dempsey in the film In the Mood. The couple divorced in 1994.

On July 31, 1999, Dempsey married Jillian Fink. The couple have three children, daughter Tallulah Fyfe (born 20 February 2002) and twin sons Sullivan Patrick and Darby Galen (born 1 February 2007). The family resides in Malibu and also has homes in Maine and Texas. Dempsey was diagnosed with dyslexia at age 12. As a result, it is necessary for him to memorize all his lines in order to perform, even for auditions where he was unlikely to get the part. Entertainment Weekly put Dempsey's hair on its end-of-the-decade "best-of" list, saying, "What made Grey's Anatomy a mega-medi-hit? It could have something to do with creator Shonda Rhimes' scalpel-sharp writing…or McDreamy's impossibly luxurious mane. Just saying." In 1997, Dempsey's mother was diagnosed with ovarian cancer. She was treated for the disease and had two relapses and had it treated another two times. In response to his mother's bouts with cancer, Dempsey helped start the Patrick Dempsey Center at Central Maine Medical Center in his home town of Lewiston, Maine. In October 2009 when Dempsey introduced the first Dempsey Challenge, registration was closed after reaching the goal of 3,500 cyclists, runners and walkers. The event raised more than one million dollars for the cancer center. His mother was in the crowd as Dempsey finished his 50-mile ride. The Challenge has since become an annual October event presented by Amgen in the Lewiston-Auburn area.

Patrick Dempsey cool and handsome pose

Patrick Dempsey cool pose